Tag Archive: Research


Fifty years ago the first plastic wrapped sandwich loaf was created in Chorleywood. Since then it has spread across the world; David Sillito is now asking if this was a design classic or a crime against bread.gn classic or a crime against bread, asks David Sillito.

It is estimated that more than 80% of all loaves in Britain are now made the Chorleywood way. The work of the scientists at the Chorleywood Flour Milling and Bakery Research Association laboratories in 1961 led to a new way of producing bread, making the average loaf in Britain 40% softer, reducing its cost and more than doubling its life. The bread scientist, Stan Cauvain, who worked with the original inventors and has written the definitive work on the Chorleywood Process says they knew from the beginning they had changed baking forever.

Its origins lay in the late 1950s and the need to try to find a way for small bakers to compete with new industrial bakeries. The light brown “national loaf” during the long years of rationing had, for many consumers, outstayed its welcome. Soft, springy, white bread – that did not go stale quickly – was what the public wanted.

Already, thanks to the Chorleywood process, nearly half the wheat in our bread is British. The industry’s current development programme could bring about a situation where British bread is made from an even higher proportion of British wheat – thus making the British loaf even better value for money in relation to world bread prices.

The research bakers at Chorleywood discovered that by adding hard fats, extra yeast and a number of chemicals and then mixing at high speed you got a dough that was ready to bake in a fraction of the time it normally took. It allowed bread to be made easily and economically with low protein British wheat.
But with industrial bakers quickly adopting the process, rather than helping small bakeries, the research at Chorleywood helped put thousands of them out of business. For some bread lovers, particularly the “artisan bread movement” anything Chorleywood is simply not real bread. “This stuff is like cotton wool,” says Paul Barker, who himself used to work as an industrial baker and sold the emulsifiers, enzymes and other chemicals used in modern baking.

The classic white loaf – how it is made and what people think of it

The issue he says is about both taste and digestion. “Modern bread doesn’t taste of bread,” he says. “If it’s not allowed to rise and prove naturally then it doesn’t develop the proper taste.” There is also the matter of health. The Chorleywood loaf has twice the amount of yeast of a traditional loaf, it has enzymes and oxidants added and while certain chemical additives such as potassium bromate have been banned, Paul Barker and other bread campaigners believe it is behind the growth in the number of people who struggle to digest bread.

“Every day I have people who say they have given up eating bread and then find they don’t have a problem with bread that’s been allowed to develop slowly. My sourdough takes more than 70 hours to make.” Proving this, however, is another matter. Prof John Warner at Imperial College in London says there has been a marked increase in allergies and intolerance of wheat and bread over the last 50 years, just as there has been an increase in allergies to dust, nuts and dozens of other items.

  • 1928: First bread slicing machine, invented by Otto Rohwedder, exhibited at a bakery trade fair in the US
  • 1930: Large UK bakeries take commercial slicers and sliced bread first appears in shops
  • 1933: Around 80% of US bread is pre-sliced and wrapped. The phrase “the best thing since sliced bread” coined
  • 1941: Calcium added to UK flour to prevent rickets
  • 1942: The national loaf – much like today’s brown loaf – introduced to combat shortage of white flour
  • 1954: Conditions in bakeries regulated by the Night Baking Act
  • 1956: National loaf abolished
  • 1961: The Chorleywood Bread Process introduced
  • However, three-quarters of people who believe they have an allergy or medical intolerance to bread show no signs of any symptoms in blind testing. He, himself, though is wary of what sort of bread he eats. “We have several pounds of bacteria in our guts and there have been marked changes in this gut flora in affluent societies over the last 50 years.” While producers are not obliged to say what enzymes are added to the bread, Polson says there is no evidence that it is any harder to digest. “There are some additional additives to give it a bit more shelf life, a bit of extra softness – but all it’s doing is augmenting what is happening in the natural process.” So, the Chorleywood process has its critics but its success with consumers is undeniable. Even in France some stick loaves are now made the Chorleywood way, although not the classic “baguette”.

    The process is now used in more than 30 countries with Colombia and Ecuador taking it on in the last few years. Britain’s white bread market is worth about £1bn a year, and most of that is Chorleywood bread. It’s cheap, filling, soft, long-lasting and, because it can turn low-protein British wheat in to palatable bread, a boon to British farmers. While it’s considered by researchers at the food technology research institute in Chipping Campden to be a marvel of food engineering – the public does not seem to value it too highly.

    Almost a third of the bread bought in Britain – 680,000 tonnes a year – is thrown away.

When guest-editing Radio 4′s Today Programme in December 2010, Colin Firth commissioned a studyd as one of four co-authors of an academic paper into human brains. He asked scientists to scan the brains of politicians to see if there was any difference dependent on political leaning. Publish is the the journal Current Biology the paper was hailed as a “useful contribution”.

Initially the brains of Conservative Alan Duncan and Labour’ Stephen Pound were scanned by Geraint Rees, from University College London’s Institute of Cognitive Neuroscience. The research was continued with replicationanother 90 participants; the scan showed an association between thicker areas within the brain and Liberal and Conservative attitudes. Following a repeat of the study researchers found that they were able to predict political leaning from a brain scan with 72% accuracy.

“It is a useful contribution because it builds on and extends previous work.” This is is a quote from New York University’s Professor John Jost, one of the world’s leading authorities in political psychology.”It will probably be several years before we understand the full meaning of these results. In the meantime, the field of political neuroscience could do worse than having Colin Firth as a scientific ambassador.”

Smoking damages the body in minutes rather than years, according to research in the US. A report, published in Chemical Research in Toxicology, shows that chemicals which cause cancer form rapidly after smoking. Scientists involved in the small-scale study described the results as a stark warning to people considering smoking. Anti-smoking charity Ash described the research as “chilling” and as a warning that it is never too early to quit.

The long term impact of smoking, from heart disease to a range of cancers, is well known. This study suggests the damage begins just moments after the first cigarette is smoked.The researchers looked at the level of chemicals linked with cancer, polycyclic aromatic hydrocarbons (PAH), in 12 patients after smoking. A PAH was added to the subject’s cigarettes, which was then modified by the body and turned into another chemical which damages DNA and has been linked with cancer.

The research shows this process only took between 15 and 30 minutes to take place. Professor Stephen Hecht, from the University of Minnesota, said: “This study is unique, it is the first to investigate human metabolism of a PAH specifically delivered by inhalation in cigarette smoke, without interference by other sources of exposure such as air pollution or the diet. The results reported here should serve as a stark warning to those who are considering starting to smoke cigarettes. Martin Dockrell, director of policy and research at Ash (Action on Smoking and Health), said: “Almost everybody knows that smoking can cause lung cancer.

“The chilling thing about this research is that it shows just how early the very first stages of that process begin – not in 30 years but within 30 minutes of a single cigarette for every subject in the study. “The process starts early but it is never too late to quit and the sooner you quit the sooner you start to reduce the harm.”

SWOT
• STRENGTHS
• WEAKNESSES
• OPPORTUNITIES
• THREATS
Analysing these gives businesses an overview of their position in relation to their external environment. The strengths and weaknesses of a business arise from its internal environment; that is, resources and their use, structure, culture and the different business functions. Which strengths a business decides to build upon and which it seeks to minimise depends on the impact of opportunities and threats from the external environment. Once the external influences on a business have been identified, they can then be judged to be either a threat or an opportunity and can be dealt with, or taken advantage of, as appropriate.

One method of undertaking a SWOT analysis is to consider strengths, weaknesses opportunities and threats in relation to four key business functions: marketing, operations, human resources and finance.

UK researchers claim that antidepressants get to work immediately to lift mood, contrary to current belief.
The researchers state that although patients may not notice the effects until months into the therapy, they work subconsciously. According to Oxford University Researchers the action is rapid, occuring within hours of taking the drugs.

Dr Michael Thase, a psychiatrist from the University of Pennsylvania, said the findings challenged conventional wisdoms and were potentially “paradigm-changing”. “The highest research priority is to confirm that the rapid effects observed in this study are predictive of eventual clinical benefit.”

He said it was possible that switching off the negative thoughts was a crucial part of the therapy.

Alternatively, it might merely be a sign that the drug was beginning to work at the cell level in the brain.

Paul Farmer, chief executive of Mind, said: “This research may contribute to our understanding of how our bodies respond to antidepressants, but the changes recorded can’t always be felt by patients and it can be some weeks before they begin to feel the symptoms of depression easing.

“We must also remember that the side-effects of medication can often be felt straight away long before the benefits really kick in, and this will always affect people’s experiences in the initial stages of treatment.”

Over 50% of adults feel that school sciences lessons should teach both evolutionary theory and creationism alongside each other. The survey was carried out in 10 countries which were:

  • Argentina
  • China
  • Egypt
  • Great Britain
  • India
  • Mexico
  • Russia
  • South Africa
  • Spain
  • USA

Of those surveyed over 7,000 knew of Darwin’s work already. In the survey people were asked which statements were closest to their own opinion about how evolutionary theories should be taught in science lessons in schools. The highest proportion agreeing that evolutionary theories alone should be taught was in India, at 49%, followed by Spain (42%).

Darwinism is a controversial theory as it challenges religious explanation for life on earth. However it seems that alot of people feel that it is good to have the two opposing theories taught alongside each other which would suggest that society has progressed and nows feels that both theories are valid and have equal credibility. It shows a tollerance of differences, this could be due to the fact that due to immigration and now countries are becoming more multicultural, if you attempted to teach all of the religious theories it would take a very long time.

Research has suggested that a drug used to treat cancer can stop contractions and may prevent premature labour. This research was carried out by a team from Newcastle University, they tested the drug Trichostatin A on tissue taken from 36 women undergoing a caesarean. They claim that it worked by increasing the levels of a protein that controls muscle relaxation.

Preterm labour and birth is the single biggest cause of death in infants in the developed world, around 1,500 babies die in the UK every year. There are a number of drugs which are used to attempt to stop early labour but research has shown them to have serious side effects.

The researchers got permission to take samples of the muscles of women undergoing caesarean sections at the Royal Victoria Infirmary in Newcastle. They exposed the muscle to TSA, a drug used to treat cancer, and measured the effects on both spontaneous contractions and those induced by the labour drug, oxytocin.
They recorded an average 46% reduction in contractions for the spontaneously contracting tissue and an average 54% reduction in the oxytocin induced contractions.

Professor Jane Norman, a spokeswoman for the Royal College of Obstetrics and Gynaecology (RCOG), said: “At the moment, it’s not possible to treat preterm labour effectively. We only have drugs that delay it by 24 hours or so – not enough to deliver the baby safely. There are experts who say that until doctors understand the cause of premature labour there is no way to develop a successful a treatment.

Of course as with any research there are those who feel that premature labour and birth can’t be or shouldn’t be prevented as the body has started labour early for a reason therefore doctors shouldn’t mess with nature. However mothers who have lost a baby because they were born prematurely would disagree and would claim that their child’s life should have been saved.

A study done by the University of Kansa suggests that failing memory may not be the first signal for the onset of Alzheimer’s disease. Their research showed that a decline in thinking and learning skills may be warning signs years before a diagnosis, it is thought that spatial skills, those used for completing jigsaws are the first to fail.

This research holds the key as current drugs are more likely to have a significant impact if given when the disease is still in its early stages. It is thought that approximately 700,000 people in the UK have dementia, with levels expected to soar in coming years as the population ages.

If techniques can be developed in order to detect the disease when it’s in the early stages, it can dramatically improve the quality of life for those who suffer from dementia and those who care for them. However, there is still the potential for it to have a negative impact as some people may become depressed and could also potentially be misdisagnosed. In some cases ignorance is bliss.

American researchers have found that children can be taught to use their imagination to tackle frequent bouts of abdominal pain. It is thought that the technique works particularly well due to their fertile imaginations. The research suggests that 1 in 5 children suffer with frquent abdominal pain with no identifiable cause. There were 30 children aged between 6 and 15 in the study half had 20 minute sessions of “guided imagery” this is where the patient is prompted to imagine things which will reduce their discomfort. The other half had the mainstream care.

It is thought that the treatment is very positive because it is inexpensive and is able to be self administered, which potentially opens the door for easily enhancing treatment outcomes for a lot of children sufering from frequent stomach aches.

This technique is an amazing breakthrough because this means that children can be treated by other means instead of drugs which is definately a positive. Also it means that more children can be treated without massive waiting lists which can be a definate plus for the NHS and the parents of the children who are suffering from abdominal pain and there is nothing they can do

In order to get some psychiatric patients to take their medication doctors are resorting to paying them. A trial involving 68 patients suffering from either bipolar or schizophrenia was carried out and the patients received £15 for every jab of anti-psychotic drug. If they take all of their medication they could potentially get £720 a year.

However there is opposition to this proposal; the charity, Mind feel that people should take the medication for health benefits not money.

Statististics show that patients not taking their medication is a big problem and increases relapse risk and NHS costs. It is estimated 33% of schizophrenics fail to take their prescribed medication. Professor Priebe, one of the experts conducting the study explains that they chose £15 as it is a small amount which they think will act as an incentive.

It is thought that patients who miss 1-10 days of oral anti-psychotic therapy are at greater risk of a patient being admitted to hospital, they say. The statistics show that this increase is nearly double that of a patient who never misses a day.

Whilst this concept seems like a good idea to an extent, it is not without it’s problems such as patients disregarding their well being in exchange for cash. Also although the drugs are only administered to those who need them it will put more financial strain on the NHS. If a patient refuses to take the oral medication that is their choice. As the saying goes you can lead a horse to water but you can’t make it drink.
If a patient is incapable of taking the medication then measures should be taken to rectify this, but I don’t agree with paying somebody to take their medication.